This is the list of all the superheroes who have fought Doctor Doom in the issues covered by the retrospective so far.
A few ground rules:
1) The story is in continuity. Sadly this leaves out Superman and Santa Claus.
2) Doctor Doom has to fight the hero, not simply meet him. Fighting a Doombot or one of Doom’s minions still counts.
3) It goes without saying, but it has to be a superhero. Anti-heroes and vigilantes will probably make the cut, but people like Nick Fury are not included.
| # | Hero | Issue | Era |
| 1 | Mr. Fantastic | Fantastic Four #5 | 60s |
| 2 | Thing | Fantastic Four #5 | 60s |
| 3 | Invisible Girl | Fantastic Four #5 | 60s |
| 4 | Human Torch | Fantastic Four #5 | 60s |
| 5 | Hank Pym | Fantastic Four 16 | 60s |
| 6 | Spider-Man | Amazing Spider-Man 5 | 60s |
| 7 | Wasp | Avengers #1.5, chronologically SVTU #9 | 60s (continuity insert) |
| 8 | Thor | Avengers #1.5, chronologically Thor #182 | 60s (continuity insert) |
| 9 | Iron Man | Avengers #1.5, chronologically SVTU #9 | 60s (continuity insert) |
| 10 | Hulk | Avengers #1.5, chronologically Hulk #143 | 60s (continuity insert) |
| 11 | Daredevil | Fantastic Four 39 | 60s |
| 12 | Captain America | Avengers 25 | 60s |
| 13 | Hawkeye | Avengers 25 | 60s |
| 14 | Scarlet Witch | Avengers 25 | 60s |
| 15 | Quicksilver | Avengers 25 | 60s |
| 16 | Silver Surfer | Fantastic Four 57 | 60s |
| 17 | Crystal | Fantastic Four 84 | 60s |
| 18 | Namor | Sub-Mariner #20 | 70s |
| 19 | Black Panther | Astonishing Tales #6 | 70s |
| 20 | Luke Cage | Hero for Hire #8 | 70s |
| 21 | Medusa | Fantastic Four #143 | 70s |
| 22 | Shroud | Super-Villain Team-Up #7 | 70s |
| 23 | Vision | Super-Villain Team-Up #9 | 70s |
| 24 | Namorita | Super-Villain Team-Up #9 | 70s |
| 25 | Beast | Avengers #156 | 70s |
| 26 | Wonder Man | Avengers #156 | 70s |
| 27 | Ghost Rider | Champions #16 | 70s |
| 28 | Shang-Chi | Master Of Kung Fu #60 | 70s |
| 29 | Cyclops | WGCM #11, chronologically Secret Wars #11 | 70s (continuity insert) |
| 30 | Jean Grey | WGCM #11, chronologically Fantastic Four #312 | 70s (continuity insert) |
| 31 | Havok | WGCM #11 | 70s (continuity insert) |
| 32 | Polaris | WGCM #11 | 70s (continuity insert) |
| 33 | Professor X | WGCM #11, chronologically Secret Wars #11 | 70s (continuity insert) |
| 34 | Black Bolt | WGCM #12, chronologically Fantastic Four #375 | 70s (continuity insert) |
| 35 | Karnak | WGCM #12, chronologically Daredevil #278 | 70s (continuity insert) |
| 36 | Gorgon | WGCM #12, chronologically Daredevil #278 | 70s (continuity insert) |
| 37 | Triton | WGCM #12, chronologically Fantastic Four #375 | 70s (continuity insert) |
| 38 | Blade | Blade v5 #2 | Continuity insert |
| 39 | Dazzler | Dazzler #3 | 80s |
| 40 | Storm | Uncanny X-Men #145 | 80s |
| 41 | Colossus | Uncanny X-Men #145 | 80s |
| 42 | Wolverine | Uncanny X-Men #145 | 80s |
| 43 | Nightcrawler | Uncanny X-Men #145 | 80s |
| 44 | Angel | Uncanny X-Men #145 | 80s |
| 45 | Acroyear | Micronauts #41 | 80s |
| 46 | Arcturus Rann | Micronauts #41 | 80s |
| 47 | Bug | Micronauts #41 | 80s |
| 48 | Devil | Micronauts #41 | 80s |
| 59 | Marionette | Micronauts #41 | 80s |
| 50 | Captain Marvel II | Secret Wars #10 | 80s |
| 51 | Spider-Woman II | Secret Wars #11 | 80s |
| 52 | Rogue | Secret Wars #11 | 80s |
| 53 | War Machine | Secret Wars #11 | 80s |
| 54 | She-Hulk | Secret Wars #11 | 80s |
| 55 | Tigra | Emperor Doom | 80s |
| 56 | Mockingbird | Emperor Doom | 80s |
| 57 | Starfox | Emperor Doom | 80s |
| 58 | Machine Man | Emperor Doom | 80s |
| 59 | Cloak | Cloak & Dagger #10 | 80s |
| 60 | Dagger | Cloak & Dagger #10 | 80s |
| 61 | She-Thing | Fantastic Four #311 | 80s |
| 62 | Iceman | Fantastic Four #312 | 80s |
| 63 | Hercules | Thor #409 | 80s |
| 64 | Doctor Strange | Amazing Spider-Man Annual #14 | 80s |
| 65 | Quasar | Avengers #311 | 80s |
| 66 | Punisher | Punisher #28 | 80s |
| 67 | Alex Power | Power Pack #53 | 80s |
| 68 | Jack Power | Power Pack #53 | 80s |
| 69 | Julie Power | Power Pack #53 | 80s |
| 70 | Katie Power | Power Pack #53 | 80s |
| 71 | Sandman | Avengers #332 | 90s |
| 72 | Rage | Avengers #333 | 90s |
| 73 | Kitty Pride | Excalibur #37 | 90s |
| 74 | Captain Britain | Excalibur #37 | 90s |
| 75 | Rachel Summers | Excalibur #37 | 90s |
| 76 | Meggan | Excalibur #37 | 90s |
| 77 | Squirrel Girl | Marvel Super-Heroes #8 | 90s |
| 78 | Ghost Rider II | Marvel Comics Presents #100 | 90s |
| 79 | Moon Knight | Moon Knight #39 | 90s |
| 80 | Adam Warlock | Infinity War #5 | 90s |
| 81 | Lyja | Fantastic Four #375 | 90s |
| 82 | Psi-Lord | Fantastic Four #381 | 90s |
| 83 | Deathlok II | Deathlok #2 | 90s |
| 84 | Misty Knight | Deathlok #2 | 90s |
| 85 | Forge | Deathlok #2 | 90s |
| 86 | Coldblood | Deathlok #3 | 90s |
| 87 | Jubilee | Deathlok #5 | 90s |
| 88 | Nova | Nova v2 #11 | 90s |
| 89 | Ant-Man II | Nova v2 #11 | 90s |
| 90 | Cable | Cable #63 | 90s |
| 91 | Gambit | Gambit vol.3 #12 | 90s |
| 92 | Bucky (Rikki) | Thunderbolts #52 | 2000s |
| 93 | Toro II | Thunderbolts #52 | 2000s |
| 94 | Speedball | Penance: Relentless#4 | 2000s |
| 95 | Ares | Mighty Avengers #9 | 2000s |
| 96 | Black Widow | Mighty Avengers #9 | 2000s |
| 97 | Captain Marvel III | Mighty Avengers #9 | 2000s |
| 98 | Sentry | Mighty Avengers #9 | 2000s |
| 99 | Doctor Voodoo | Doctor Voodoo #1 | 2000s |
| 100 | M | X-Factor #202 | 2000s |
| 101 | Shatterstar | X-Factor #202 | 2000s |
| 102 | Shuri | Doomwar #1 | 2010s |
| 103 | Psylock | Doomwar #1 | 2010s |
